{"product_id":"l-carnitine","title":"L-Carnitine 500mg","description":"\u003ch3 class=\"text-text-100 mt-2 -mb-1 text-base font-bold\"\u003eL-Carnitine (Levocarnitine) | Quaternary Ammonium Compound | Research Grade\u003c\/h3\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eFull Name:\u003c\/strong\u003e L-Carnitine (Levocarnitine) \u003cstrong\u003eAlso Known As:\u003c\/strong\u003e Vitamin BT \u003cstrong\u003eClass:\u003c\/strong\u003e Quaternary ammonium \/ L-amino-acid derivative \u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e C₇H₁₅NO₃ \u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 161.20 g\/mol \u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;99% (HPLC verified) \u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilised powder \u003cstrong\u003eAvailable Size:\u003c\/strong\u003e 500mg \u003cstrong\u003eCAS Number:\u003c\/strong\u003e 541-15-1\u003c\/p\u003e\n\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003ch3 class=\"text-text-100 mt-2 -mb-1 text-base font-bold\"\u003eWhat Is L-Carnitine?\u003c\/h3\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eL-Carnitine (Levocarnitine; CAS 541-15-1) is a naturally occurring quaternary ammonium compound biosynthesised from lysine and methionine. It is supplied here as a lyophilised research compound at greater than 99% purity for laboratory use. Structurally, L-Carnitine carries a permanently positive charge at physiological pH — a property that governs its membrane transport via the organic cation\/carnitine transporter OCTN2 (SLC22A5) and distinguishes it from free amino-acid analogues.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eIts canonical biological role centres on the mitochondrial carnitine shuttle: long-chain acyl-CoA esters cannot cross the inner mitochondrial membrane directly. Carnitine palmitoyltransferase I (CPT1) at the outer mitochondrial membrane esterifies them to acylcarnitines; the acylcarnitine translocase (SLC25A20) carries the acylcarnitine across; and CPT2 at the inner membrane regenerates the acyl-CoA for β-oxidation. This shuttle is the rate-limiting gateway for long-chain fatty-acid entry into the mitochondrial matrix, making L-Carnitine a central research tool in studies of mitochondrial fuel selection and metabolic flexibility.\u003c\/p\u003e\n\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003ch3 class=\"text-text-100 mt-2 -mb-1 text-base font-bold\"\u003eResearch Context\u003c\/h3\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eMitochondrial Stress Assays (Seahorse XF)\u003c\/strong\u003e L-Carnitine is a standard supplement in Seahorse XF Mito Fuel Flex and fatty acid oxidation assays. The Seahorse Fatty Acid Oxidation (FAO) assay requires L-Carnitine co-supplementation with long-chain fatty acids (palmitate–BSA) to enable mitochondrial import via CPT1. Without exogenous L-Carnitine, long-chain substrate utilisation is substantially limited in many cell lines, making it indispensable for accurate measurement of mitochondrial fatty-acid oxidation capacity.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eAcylcarnitine Profiling\u003c\/strong\u003e Research into carnitine-shuttling defects and mitochondrial fatty acid oxidation (FAO) disorders typically relies on mass-spectrometric acylcarnitine profiling of conditioned media or cell lysates. L-Carnitine at defined research concentrations enables researchers to generate acylcarnitine profiles in cell-based models, study CPT1 isoform selectivity, and model carnitine transporter (OCTN2\/SLC22A5) function.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eCellular Energy Metabolism\u003c\/strong\u003e Researchers studying mitochondrial biogenesis, fuel-switching, or metabolic flexibility in skeletal muscle myotubes, hepatocytes, and cardiomyocyte models routinely use exogenous L-Carnitine to ensure sufficient carnitine availability in serum-free or carnitine-depleted culture contexts.\u003c\/p\u003e\n\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003ch3 class=\"text-text-100 mt-2 -mb-1 text-base font-bold\"\u003eProduct Specifications\u003c\/h3\u003e\n\u003cdiv class=\"overflow-x-auto w-full px-2 mb-6\"\u003e\n\u003ctable class=\"min-w-full border-collapse text-sm leading-[1.7] whitespace-normal\"\u003e\n\u003cthead class=\"text-left\"\u003e\n\u003ctr\u003e\n\u003cth scope=\"col\" class=\"text-text-100 border-b-0.5 border-border-300\/60 py-2 pr-4 align-top font-bold\"\u003eSpecification\u003c\/th\u003e\n\u003cth scope=\"col\" class=\"text-text-100 border-b-0.5 border-border-300\/60 py-2 pr-4 align-top font-bold\"\u003eDetail\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eCompound\u003c\/td\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eL-Carnitine (Levocarnitine)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eAlso Known As\u003c\/td\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eVitamin BT, Levocarnitine\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eClass\u003c\/td\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eQuaternary ammonium \/ L-amino-acid derivative\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eMolecular Formula\u003c\/td\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eC₇H₁₅NO₃\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eMolecular Weight\u003c\/td\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003e161.20 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eCAS Number\u003c\/td\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003e541-15-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003ePubChem CID\u003c\/td\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003e10917\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003ePurity\u003c\/td\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003e\u0026gt;99% (HPLC verified)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eForm\u003c\/td\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eLyophilised powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eAppearance\u003c\/td\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eWhite lyophilised powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eSolubility\u003c\/td\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eFreely soluble in water\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eVial Size\u003c\/td\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003e500mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eStorage (lyophilised)\u003c\/td\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eSealed vial — cool, dark conditions (\u0026lt;25°C)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003eStorage (reconstituted)\u003c\/td\u003e\n\u003ctd class=\"border-b-0.5 border-border-300\/30 py-2 pr-4 align-top\"\u003e2–8°C; aliquot to avoid repeated freeze-thaw\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003ch3 class=\"text-text-100 mt-2 -mb-1 text-base font-bold\"\u003eHandling \u0026amp; Storage\u003c\/h3\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eL-Carnitine lyophilised powder is freely soluble in sterile water. For in-vitro assays, reconstitute in the appropriate aqueous buffer (PBS or assay media) immediately before use. Once reconstituted, aliquot and store at 2–8°C; avoid prolonged exposure to elevated temperatures. Keep the sealed vial in a cool, dark environment until use. All handling should comply with standard laboratory safety protocols and applicable institutional guidelines.\u003c\/p\u003e\n\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003ch3 class=\"text-text-100 mt-2 -mb-1 text-base font-bold\"\u003eCertificate of Analysis\u003c\/h3\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eEvery batch of our L-Carnitine is independently tested and supplied with a Certificate of Analysis confirming purity by HPLC. Batch L7392 — Exp. 05\/2029. Available on request and via the Nexyra Lab COA verification portal.\u003c\/p\u003e\n\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003ch3 class=\"text-text-100 mt-2 -mb-1 text-base font-bold\"\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003eImportant Notice\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003eThis product is intended strictly for in vitro research and laboratory use only. L-Carnitine supplied by Nexyra Lab is not approved for human or veterinary use by the FDA, EMA, or any other regulatory authority in this form. It is not a drug, supplement, or food product. This product must not be administered to humans or animals. By purchasing this product, the buyer confirms they are a qualified researcher and will use the compound solely for lawful scientific research purposes.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"NEXYRALAB","offers":[{"title":"500mg","offer_id":60064321306958,"sku":"NEX-LCARN-500","price":19.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1035\/3351\/0990\/files\/l-carnitine-navy-v2_0d9feb64-5fc4-43ef-8cf0-07091e4cee64.png?v=1783446101","url":"https:\/\/checkout.nexyralab.com\/products\/l-carnitine","provider":"Nexyralab.com","version":"1.0","type":"link"}